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-GCS/GS Are Intracellular Producers of -Glutamyl Peptides -GCS and GS are generally understood to work together for the purpose of glutathione synthesis, but uncoupling could occur between these enzymes
Chem Res Toxicol 21 : 10111016 Harwood DT, Kettle AJ, Brennan S, Winterbourn CC 2009 Simultaneous determination of reduced glutathione, glutathione disulphide and glutathione sulphonamide in cells and physiological fluids by isotope dilution liquid chromatography-tandem mass spectrometry
Potential interventions to mitigate immunosenescence, including reshaping immune organs, targeting different immune cells or signaling pathways, and nutritional and lifestyle interventions, are summarized